Developages - Development and Technology Blog

Ars Technica reports on research out of Cal Tech where scientists were able to create logic gates out of RNA molecules. Thus far, they’ve demonstrated AND gates and OR gates, with work proceeding on more complicated systems. The work shows promise for ability to easily detect the presence of particular chemicals. The abstract from the scientists’ paper is available at Science. Quoting Ars: “Detecting tetracycline isn′t especially interesting, but RNA that binds to specific small molecules is actually relatively easy to make; repeated rounds of amplification and selection for binding can evolve these RNAs in a couple of days. This means that, in a matter of days, researchers can grow yeast colonies that glow in response to a variety of chemicals, or even to combinations of chemicals. More complicated circuits should be possible if the ribozymes are inserted into messenger RNAs that encode transcription factors, which could, in turn, regulate genes that encode yet other ribozymes.”

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Original post by Soulskill

AliasMarlowe writes “Stanley Miller performed the famous experiments in the 1950s showing that amino acids and other building blocks for biomolecules could be produced by passing lightning through a mix of simple hydrocarbons, water vapor, and ammonia (thought at the time to approximate the Earth’s early atmosphere). Other experiments approximated the environment around volcanic eruptions, but those results were not published. Following his death last year, a former student discovered the materials from those experiments, in labelled vials. Analysis of this material indicates that the conditions around volcanic eruptions (still thought to be representative of such events in the early Earth) resulted in a higher yield of amino acids than the simple lightning experiments, and resulted in a greater variety of amino acids.” Pharyngula has a discussion of the Science paper, including a graph of the amino acids produced.

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Original post by kdawson

GalaticGrub writes “A pair of paralyzed monkeys regained the ability to move their arms after researchers wired individual neurons to the monkey’s arm muscles. A team of researchers at the University of Washington temporarily paralyzed each monkey’s arm then rerouted brain signals from a single neuron in the motor cortex around the blocked nerve pathway via a computer. The neuron fired above a certain rate, the computer translated the signal into a jolt of electricity to the arm muscle, causing it to contract. The monkeys practiced moving their arms by playing a video game.”

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Original post by samzenpus

FiReaNGeL writes “Researchers conducted a genome-wide association study of 1,125 Caucasian men who had been assessed for male pattern baldness. They found two previously unknown genetic variants on chromosome 20 that substantially increased the risk of male pattern baldness. They then confirmed these findings in an additional 1,650 Caucasian men. ‘If you have both the risk variants we discovered on chromosome 20 and the unrelated known variant on the X chromosome, your risk of becoming bald increases sevenfold. What’s startling is that one in seven men have both of those risk variants.’” So maybe gene therapy will finally have a real purpose.

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Original post by timothy

GogglesPisano writes “UK geneticist Steve Jones gave a presentation entitled Human Evolution Is Over. He asserts that human beings have stopped evolving because modern social customs have lowered the age at which human males have offspring, which results in fewer of the mutations necessary to drive evolutionary change. Apparently the fate of our species now depends upon older guys hooking up with younger woman. I, for one, welcome this development.”

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Original post by samzenpus

Iddo Genuth writes “The Royal Swedish Academy of Sciences has announced three recipients of the Nobel Prize in Chemistry award for 2008: jointly given to Osamu Shimomura, Martin Chalfie and Roger Y. Tsien ‘for the discovery and development of the green fluorescent protein, GFP’ — a remarkable brightly glowing green fluorescent protein first observed in the beautiful jellyfish, Aequorea victoria, in 1962.”

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Original post by timothy

Hugh Pickens writes “For more than a century, ranchers in the West have kept cattle in place with fences of barbed wire, split wood and, more recently, electrified wires. Now animal science researchers with the Department of Agriculture, is working on a system that will allow cowboys to herd their cattle remotely via radio by singing commands and whispering into their ears and tracking movements by satellite and computer. A video of Dean Anderson, a researcher at the USDA’s Jornada Experimental Range at Las Cruces, NM., shows how he has built radios that attach to an animal’s head that allow a person at the other end to issue a range of commands — gentle singing, sharp commands, or a buzz like a bee or snake — to get the cattle to move where one wants them to. Anderson says it would cost $900 today to put a radio device on one head of cattle, but he says costs will fall and the entire herd wouldn’t have to be outfitted, just the “leaders.” Much of the research has focused on how cattlemen can identify which cattle in their herds are the ones that the others follow.”

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Original post by CmdrTaco

Iddo Genuth writes to tell us that a researcher from Tel Aviv University is exploring the possibility that humans may be able to “see” via their skin. Professor Leonid Yaroslavsky hopes to utilize this possible technology to find solutions for the blind in addition to new types of image capture that might be able to work where conventional lenses fail. Unfortunately he has a long uphill battle ahead to convince others that his theories are possible. “The lenses currently used for optics-based imaging have many problems. They only work within a limited range of electromagnetic radiation. Relatively, these are still costly devices greatly limited by weight and field of view. The imaging Professor Yaroslavsky has in mind has no lenses and he believes the devices can be adapted to any kind of radiation and wavelength. They could essentially work with a 360-degree field of view and their imaging capability will only be determined by computer power rather than the laws of light diffraction.”

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Original post by ScuttleMonkey

Iddo Genuth writes “Researchers at the Surface Science Laboratory at Universidad Autonoma de Madrid have created an ultrasmooth mirror that could be used to create a revolutionary new atomic microscope within the next several years. The new atomic microscope — using helium atoms for imaging — has the potential to provide the same resolution as existing electron microscopes but without many of the problems which have plagued them for years.”

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Original post by kdawson

Aditya Malik writes “Wired has an interesting story up about how a lab led by Jack Szostak, a molecular biologist at Harvard Medical School, is building ‘protocells’ from artificial molecules which are very close to satisfying the conditions for being ‘alive’. ‘Szostak’s protocells are built from fatty molecules that can trap bits of nucleic acids that contain the source code for replication. Combined with a process that harnesses external energy from the sun or chemical reactions, they could form a self-replicating, evolving system that satisfies the conditions of life, but isn’t anything like life on earth now, but might represent life as it began or could exist elsewhere in the universe.’ This obviously raises some questions about creationism, not to mention some scary bio-research-gone-wild scenarios.”

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Original post by Soulskill

quinnlynn writes “A group of research scientists at Yale discovered that the evolution of opposable thumbs and upright walking in humans is due to changes in the genome in the areas still classified as “junk DNA.” Quoting: ‘Results from a comparative analysis of the human, chimpanzee, rhesus macaque and other genomes reported in the journal Science suggest our evolution may have been driven not only by sequence changes in genes, but by changes in areas of the genome once thought of as “junk DNA.” … Researchers have long suspected changes in gene expression contributed to human evolution, but this had been difficult to study until recently because most of the sequences that control genes had not been identified. In the last several years, scientists have discovered that non-coding regions of the genome, far from being junk, contain thousands of regulatory elements that act as genetic “switches” to turn genes on or off.’” Yale has also recently completed sequencing the Trichoplax genome. Trichoplax has the simplest known animal genome, and it shares 80 percent of its genes (comprised of 98 million base pairs) with humanity. Professor Stephen Dellaporta was quoted saying, “We are [excited] to find that Trichoplax contains shared pathways and defined regulatory sequences that link these most primitive ancestors to higher animal species. The Trichoplax genome will serve as a type of ‘Rosetta Stone’ for understanding the origins of animal-specific pathways.”

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Original post by Soulskill

Anti-Globalism writes “Scientists have for the first time recorded individual brain cells in the act of summoning a spontaneous memory, revealing not only where a remembered experience is registered but also, in part, how the brain is able to recreate it.”

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Original post by timothy

Calopteryx sends in a New Scientist summary of research from Sweden pointing toward the existence of a gene that influences monogamy in men. (The article doesn′t mention women, and the study subjects were all men at least 5 years into a heterosexual relationship.) “There has been speculation about the role of the hormone vasopressin in humans ever since we discovered that variations in where receptors for the hormone are expressed makes prairie voles strictly monogamous but meadow voles promiscuous; vasopressin is related to the ‘cuddle chemical’ oxytocin. Now it seems variations in a section of the gene coding for a vasopressin receptor in people help to determine whether men are serial commitment-phobes or devoted husbands.”

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Original post by kdawson

Ostracus writes to share a new take on the word “treehouse.” Engineers and plant scientists from Tel Aviv have taken the application of tree shaping to the next level, designing everything from streetlamps to houses. “A home built from trees, the researchers said, would be a natural storm protector. “After earthquakes and after tsunamis the only structures that still survive are trees,” said Yaniv Naftaly, director of operations at Plantware, a company founded in 2002. Naftaly told LiveScience the same sturdiness should apply to tree-made homes. Eshel and TAU colleague Yoav Waisel are working with Plantware to commercialize the leafy designs. The team found that certain tree species grown aeroponically (in air instead of soil and water) have roots that don’t harden. Once the malleable, so-called soft roots grow long enough in the lab, they are molded around metal frames in the shape of a playground or park bench.”

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Original post by ScuttleMonkey

Hugh Pickens writes “A Chinese medical team led by Shuzhong Guo of the Fourth Military Medical University in Xi’an has successfully completed the first transplant to include facial bone in a transplant on a man whose face was slashed by a bear. The Chinese graft included muscles, nerves, blood vessels, cartilage and skin and included an intact salivary gland, another first. Two years after the procedure, the man can eat, drink and speak, thanks to the gradual fusing of transplanted nerves and muscles with what remained of the patient’s own. This transplant together with the another ground breaking transplant last year by French doctors that removed a huge tumor that had completely infiltrated and disfigured their patient’s face, now sets the stage for a full facial transplant.”

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Original post by timothy